Next‐Generation Sequencing of Circulating Tumor DNA Reveals Frequent Alterations in Advanced Hepatocellular Carcinoma

BACKGROUND. Because imaging has a high sensitivity to diagnose hepatocellular carcinoma (HCC) and tissue biopsies carry risks such as bleeding, the latter are often not performed in HCC. Blood‐derived circulating tumor DNA (ctDNA) analysis can identify somatic alterations, but its utility has not be...

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Dettagli Bibliografici
Pubblicato in:Oncologist
Autori principali: Ikeda, Sadakatsu, Tsigelny, Igor F., Skjevik, Åge A., Kono, Yuko, Mendler, Michel, Kuo, Alexander, Sicklick, Jason K., Heestand, Gregory, Banks, Kimberly C., Talasaz, AmirAli, Lanman, Richard B., Lippman, Scott, Kurzrock, Razelle
Natura: Artigo
Lingua:Inglês
Pubblicazione: AlphaMed Press 2018
Soggetti:
Hepatobiliary
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5947459/
https://ncbi.nlm.nih.gov/pubmed/29487225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2017-0479
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