Next‐Generation Sequencing of Circulating Tumor DNA Reveals Frequent Alterations in Advanced Hepatocellular Carcinoma

BACKGROUND. Because imaging has a high sensitivity to diagnose hepatocellular carcinoma (HCC) and tissue biopsies carry risks such as bleeding, the latter are often not performed in HCC. Blood‐derived circulating tumor DNA (ctDNA) analysis can identify somatic alterations, but its utility has not be...

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Veröffentlicht in:Oncologist
Hauptverfasser: Ikeda, Sadakatsu, Tsigelny, Igor F., Skjevik, Åge A., Kono, Yuko, Mendler, Michel, Kuo, Alexander, Sicklick, Jason K., Heestand, Gregory, Banks, Kimberly C., Talasaz, AmirAli, Lanman, Richard B., Lippman, Scott, Kurzrock, Razelle
Format: Artigo
Sprache:Inglês
Veröffentlicht: AlphaMed Press 2018
Schlagworte:
Hepatobiliary
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5947459/
https://ncbi.nlm.nih.gov/pubmed/29487225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2017-0479
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