Next‐Generation Sequencing of Circulating Tumor DNA Reveals Frequent Alterations in Advanced Hepatocellular Carcinoma

BACKGROUND. Because imaging has a high sensitivity to diagnose hepatocellular carcinoma (HCC) and tissue biopsies carry risks such as bleeding, the latter are often not performed in HCC. Blood‐derived circulating tumor DNA (ctDNA) analysis can identify somatic alterations, but its utility has not be...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Ikeda, Sadakatsu, Tsigelny, Igor F., Skjevik, Åge A., Kono, Yuko, Mendler, Michel, Kuo, Alexander, Sicklick, Jason K., Heestand, Gregory, Banks, Kimberly C., Talasaz, AmirAli, Lanman, Richard B., Lippman, Scott, Kurzrock, Razelle
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2018
Assuntos:
Hepatobiliary
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5947459/
https://ncbi.nlm.nih.gov/pubmed/29487225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2017-0479
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