DNA Hydroxymethylation Levels Are Altered in Blood Cells From Down Syndrome Persons Enrolled in the MARK-AGE Project

Down syndrome (DS) is caused by the presence of part or an entire extra copy of chromosome 21, a phenomenon that can cause a wide spectrum of clinically defined phenotypes of the disease. Most of the clinical signs of DS are typical of the aging process including dysregulation of immune system. Beyo...

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Udgivet i:J Gerontol A Biol Sci Med Sci
Main Authors: Ciccarone, Fabio, Valentini, Elisabetta, Malavolta, Marco, Zampieri, Michele, Bacalini, Maria Giulia, Calabrese, Roberta, Guastafierro, Tiziana, Reale, Anna, Franceschi, Claudio, Capri, Miriam, Breusing, Nicolle, Grune, Tilman, Moreno‐Villanueva, María, Bürkle, Alexander, Caiafa, Paola
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
The Journal of Gerontology: Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5946825/
https://ncbi.nlm.nih.gov/pubmed/29069286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glx198
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