Poly(ADP-ribosyl)ation is involved in the epigenetic control of TET1 gene transcription

TET enzymes are the epigenetic factors involved in the formation of the sixth DNA base 5-hydroxymethylcytosine, whose deregulation has been associated with tumorigenesis. In particular, TET1 acts as tumor suppressor preventing cell proliferation and tumor metastasis and it has frequently been found...

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發表在:Oncotarget
Main Authors: Ciccarone, Fabio, Valentini, Elisabetta, Bacalini, Maria Giulia, Zampieri, Michele, Calabrese, Roberta, Guastafierro, Tiziana, Mariano, Germano, Reale, Anna, Franceschi, Claudio, Caiafa, Paola
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2014
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Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279378/
https://ncbi.nlm.nih.gov/pubmed/24939750
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