Загрузка...

Poly(ADP-ribosyl)ation Acts in the DNA Demethylation of Mouse Primordial Germ Cells Also with DNA Damage-Independent Roles

Poly(ADP-ribosyl)ation regulates chromatin structure and transcription driving epigenetic events. In particular, Parp1 is able to directly influence DNA methylation patterns controlling transcription and activity of Dnmt1. Here, we show that ADP-ribose polymer levels and Parp1 expression are noticea...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Ciccarone, Fabio, Klinger, Francesca Gioia, Catizone, Angela, Calabrese, Roberta, Zampieri, Michele, Bacalini, Maria Giulia, De Felici, Massimo, Caiafa, Paola
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465317/
https://ncbi.nlm.nih.gov/pubmed/23071665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046927
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!