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mRNA Cap Methyltransferase, RNMT-RAM, Promotes RNA Pol II-Dependent Transcription

mRNA cap addition occurs early during RNA Pol II-dependent transcription, facilitating pre-mRNA processing and translation. We report that the mammalian mRNA cap methyltransferase, RNMT-RAM, promotes RNA Pol II transcription independent of mRNA capping and translation. In cells, sublethal suppressio...

詳細記述

保存先:
書誌詳細
出版年:Cell Rep
主要な著者: Varshney, Dhaval, Lombardi, Olivia, Schweikert, Gabriele, Dunn, Sianadh, Suska, Olga, Cowling, Victoria H.
フォーマット: Artigo
言語:Inglês
出版事項: Cell Press 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5946721/
https://ncbi.nlm.nih.gov/pubmed/29719263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.04.004
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