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Peptide Nucleic Acids as a Tool for Site-Specific Gene Editing
Peptide nucleic acids (PNAs) can bind duplex DNA in a sequence-targeted manner, forming a triplex structure capable of inducing DNA repair and producing specific genome modifications. Since the first description of PNA-mediated gene editing in cell free extracts, PNAs have been used to successfully...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5946696/ https://ncbi.nlm.nih.gov/pubmed/29534473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23030632 |
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