Učitavanje...
Manipulating the PD-1 pathway to improve immunity
PD-1 is an inhibitory receptor induced in T cells by antigen stimulation and sustained PD-1 expression plays a key role in T cell dysfunction. Blocking PD-1 signaling rescues exhausted T cells and is an effective treatment for chronic infections and cancer. Nonetheless, combining PD-1 pathway blocka...
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| Izdano u: | Curr Opin Immunol |
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| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5946314/ https://ncbi.nlm.nih.gov/pubmed/23582509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2013.03.003 |
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