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Beyond Adjuvants: Immunomodulation strategies to enhance T cell immunity

Engagement of CD8 T cells is a crucial aspect of immune responses to pathogens and in tumor surveillance. Nonetheless most vaccination strategies with common adjuvants fail to elicit long-term memory CD8 T cells. Increased knowledge on the cellular and molecular requirements for CD8 T cell activatio...

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Bibliografische gegevens
Gepubliceerd in:Vaccine
Hoofdauteurs: Kamphorst, Alice O., Araki, Koichi, Ahmed, Rafi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449453/
https://ncbi.nlm.nih.gov/pubmed/26022562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.12.082
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