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High Glucose-Mediated Tyrosine Nitration of PI3-Kinase: A Molecular Switch of Survival and Apoptosis in Endothelial Cells

Diabetes and hyperglycemia are associated with increased retinal oxidative and nitrative stress and vascular cell death. Paradoxically, high glucose stimulates expression of survival and angiogenic growth factors. Therefore, we examined the hypothesis that high glucose-mediated tyrosine nitration ca...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Elshaer, Sally L., Lemtalsi, Tahira, El-Remessy, Azza B.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5946113/
https://ncbi.nlm.nih.gov/pubmed/29587384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox7040047
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