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Experimental Diabetes Causes Breakdown of the Blood-Retina Barrier by a Mechanism Involving Tyrosine Nitration and Increases in Expression of Vascular Endothelial Growth Factor and Urokinase Plasminogen Activator Receptor

The purpose of these experiments was to determine the specific role of reactive oxygen species (ROS) in the blood-retinal barrier (BRB) breakdown that characterizes the early stages of vascular dysfunction in diabetes. Based on our data showing that high glucose increases nitric oxide, superoxide, a...

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Autori principali: El-Remessy, Azza B., Behzadian, M. Ali, Abou-Mohamed, Gamal, Franklin, Telina, Caldwell, Robert W., Caldwell, Ruth B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868147/
https://ncbi.nlm.nih.gov/pubmed/12759255
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