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Distinct chromatin signatures of DNA hypomethylation in aging and cancer
Cancer is an aging‐associated disease, but the underlying molecular links between these processes are still largely unknown. Gene promoters that become hypermethylated in aging and cancer share a common chromatin signature in ES cells. In addition, there is also global DNA hypomethylation in both pr...
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| Pubblicato in: | Aging Cell |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5946083/ https://ncbi.nlm.nih.gov/pubmed/29504244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12744 |
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