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Global remodeling of the mouse DNA methylome during aging and in response to calorie restriction

Aging is characterized by numerous molecular changes, such as accumulation of molecular damage and altered gene expression, many of which are linked to DNA methylation. Here, we characterize the blood DNA methylome across 16 age groups of mice and report numerous global, region‐ and site‐specific fe...

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Dettagli Bibliografici
Pubblicato in:Aging Cell
Autori principali: Sziráki, András, Tyshkovskiy, Alexander, Gladyshev, Vadim N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5946071/
https://ncbi.nlm.nih.gov/pubmed/29575528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12738
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