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Global remodeling of the mouse DNA methylome during aging and in response to calorie restriction
Aging is characterized by numerous molecular changes, such as accumulation of molecular damage and altered gene expression, many of which are linked to DNA methylation. Here, we characterize the blood DNA methylome across 16 age groups of mice and report numerous global, region‐ and site‐specific fe...
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| Udgivet i: | Aging Cell |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5946071/ https://ncbi.nlm.nih.gov/pubmed/29575528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12738 |
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