NHR‐49/HNF4 integrates regulation of fatty acid metabolism with a protective transcriptional response to oxidative stress and fasting

Endogenous and exogenous stresses elicit transcriptional responses that limit damage and promote cell/organismal survival. Like its mammalian counterparts, hepatocyte nuclear factor 4 (HNF4) and peroxisome proliferator‐activated receptor α (PPARα), Caenorhabditis elegans NHR‐49 is a well‐established...

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Publicado en:Aging Cell
Main Authors: Goh, Grace Y. S., Winter, Johnathan J., Bhanshali, Forum, Doering, Kelsie R. S., Lai, Regina, Lee, Kayoung, Veal, Elizabeth A., Taubert, Stefan
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5946062/
https://ncbi.nlm.nih.gov/pubmed/29508513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12743
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