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The Caenorhabditis elegans Oxidative Stress Response Requires the NHR-49 Transcription Factor

The overproduction of reactive oxygen species (ROS) in cells can lead to the development of diseases associated with aging. We have previously shown that C. elegans BRAP-2 (Brca1 associated binding protein 2) regulates phase II detoxification genes such as gst-4, by increasing SKN-1 activity. Previo...

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Détails bibliographiques
Publié dans:G3 (Bethesda)
Auteurs principaux: Hu, Queenie, D’Amora, Dayana R., MacNeil, Lesley T., Walhout, Albertha J. M., Kubiseski, Terrance J.
Format: Artigo
Langue:Inglês
Publié: Genetics Society of America 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288832/
https://ncbi.nlm.nih.gov/pubmed/30297383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.118.200727
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