Toll-Like Receptor 2 Signaling and Current Approaches for Therapeutic Modulation in Synucleinopathies

The innate immune response in the central nervous system (CNS) is implicated as both beneficial and detrimental to health. Integral to this process are microglia, the resident immune cells of the CNS. Microglia express a wide variety of pattern-recognition receptors, such as Toll-like receptors, tha...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Caplan, Ian F., Maguire-Zeiss, Kathleen A.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945810/
https://ncbi.nlm.nih.gov/pubmed/29780321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00417
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