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Misfolded α-synuclein and toll-like receptors: therapeutic targets for Parkinson’s disease
Parkinson’s disease (PD) is typified by the loss of midbrain dopamine neurons, the presence of large proteinaceous α-synuclein-positive intracellular inclusions, oxidatively modified molecules and activated microglia. The etiology of sporadic PD is not fully understood but several lines of evidence...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3500631/ https://ncbi.nlm.nih.gov/pubmed/22166424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1353-8020(11)70008-6 |
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