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Misfolded α-synuclein and toll-like receptors: therapeutic targets for Parkinson’s disease

Parkinson’s disease (PD) is typified by the loss of midbrain dopamine neurons, the presence of large proteinaceous α-synuclein-positive intracellular inclusions, oxidatively modified molecules and activated microglia. The etiology of sporadic PD is not fully understood but several lines of evidence...

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Bibliografiska uppgifter
Huvudupphovsmän: Béraud, Dawn, Maguire-Zeiss, Kathleen A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500631/
https://ncbi.nlm.nih.gov/pubmed/22166424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1353-8020(11)70008-6
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