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Toll-Like Receptor Signaling Pathways—Therapeutic Opportunities

Toll-like receptors (TLRs) are transmembrane proteins acting mainly as sensors of microbial components. Triggering TLRs results in increased expression of multiple inflammatory genes, which then play a protective role against infection. However, aberrant activation of TLR signaling has a significant...

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Detalhes bibliográficos
Main Authors: Zhu, Jiankun, Mohan, Chandra
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963142/
https://ncbi.nlm.nih.gov/pubmed/20981241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/781235
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