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Toll-Like Receptor Signaling Pathways—Therapeutic Opportunities
Toll-like receptors (TLRs) are transmembrane proteins acting mainly as sensors of microbial components. Triggering TLRs results in increased expression of multiple inflammatory genes, which then play a protective role against infection. However, aberrant activation of TLR signaling has a significant...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Hindawi Publishing Corporation
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2963142/ https://ncbi.nlm.nih.gov/pubmed/20981241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/781235 |
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