Relationship Between Homodimeric Glucocorticoid Receptor and Transcriptional Regulation Assessed via an In Vitro Fluorescence Correlation Spectroscopy-Microwell System

Glucocorticoid receptor (GR) is a hormone-activated transcription regulatory protein involved in metabolism as well as adrenocortical responses to psychosocial stress. Ligand-activated GR localizes to the nucleus, where GR homodimers regulate gene transcription via direct binding to glucocorticoid r...

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Vydáno v:Sci Rep
Hlavní autoři: Oasa, Sho, Mikuni, Shintaro, Yamamoto, Johtaro, Kurosaki, Tsumugi, Yamashita, Daisuke, Kinjo, Masataka
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945783/
https://ncbi.nlm.nih.gov/pubmed/29748590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25393-w
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