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Screening for FtsZ Dimerization Inhibitors Using Fluorescence Cross-Correlation Spectroscopy and Surface Resonance Plasmon Analysis

FtsZ is an attractive target for antibiotic research because it is an essential bacterial cell division protein that polymerizes in a GTP-dependent manner. To find the seed chemical structure, we established a high-throughput, quantitative screening method combining fluorescence cross-correlation sp...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Mikuni, Shintaro, Kodama, Kota, Sasaki, Akira, Kohira, Naoki, Maki, Hideki, Munetomo, Masaharu, Maenaka, Katsumi, Kinjo, Masataka
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496089/
https://ncbi.nlm.nih.gov/pubmed/26154290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130933
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