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Negative Correlation between the Diffusion Coefficient and Transcriptional Activity of the Glucocorticoid Receptor

The glucocorticoid receptor (GR) is a transcription factor, which interacts with DNA and other cofactors to regulate gene transcription. Binding to other partners in the cell nucleus alters the diffusion properties of GR. Raster image correlation spectroscopy (RICS) was applied to quantitatively cha...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Mikuni, Shintaro, Yamamoto, Johtaro, Horio, Takashi, Kinjo, Masataka
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618504/
https://ncbi.nlm.nih.gov/pubmed/28841150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18091855
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