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The E3 ubiquitin ligase Triad1 influences development of Mll-Ell-induced acute myeloid leukemia

Chromosomal translocations involving the MLL1 gene characterize a poor prognosis subset of acute myeloid leukemia (AML), referred to as 11q23-AML. Transcription of the HOXA9 and HOXA10 genes is enhanced in hematopoietic stem and progenitor cells in these leukemias. We previously found the ARIH2 gene...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Wang, Hao, Bei, Ling, Shah, Chirag A., Huang, Weiqi, Platanias, Leonidas C., Eklund, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945580/
https://ncbi.nlm.nih.gov/pubmed/29459712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0131-5
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