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Experimental Asthma Persists in IL33 Receptor Knockout Mice Due to the Emergence of a TSLP-driven IL9+ and IL13+ ILC2 subpopulations

BACKGROUND: IL33 plays an important role in development of experimental asthma. OBJECTIVE: To study the role of the IL33 receptor (ST2) in persistence of asthma in a mouse model. METHODS: We studied allergen-induced experimental asthma in ST2 knockout (KO) and wild-type control mice. We measured air...

詳細記述

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書誌詳細
出版年:J Allergy Clin Immunol
主要な著者: Verma, Mukesh, Liu, Sucai, Michalec, Lidia, Sripada, Anand, Gorska, Magdalena M., Alam, Rafeul
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945345/
https://ncbi.nlm.nih.gov/pubmed/29132961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2017.10.020
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