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Distribution of pomalidomide into semen of healthy male subjects after multiple doses

OBJECTIVE: To assess whether pomalidomide can distribute into human semen and its duration in human semen. METHOD: A phase 1, randomized, double-blind, placebo-controlled study (CC-4047-CP-006) was conducted to evaluate the safety, tolerability, and pharmacokinetics of pomalidomide (CC-4047) followi...

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Bibliografiske detaljer
Udgivet i:Clin Pharmacol
Main Authors: Li, Yan, Wang, Xiaomin, Liu, Liangang, Reyes, Josephine, Palmisano, Maria, Zhou, Simon
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944449/
https://ncbi.nlm.nih.gov/pubmed/29765255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S167017
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