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An Open‐Label, Phase 1 Study to Assess the Effects of Hepatic Impairment on Pomalidomide Pharmacokinetics

Pomalidomide is an immunomodulatory drug and the dosage of 4 mg per day taken orally on days 1‐21 of repeated 28‐day cycles has been approved in the European Union and United States to treat patients with relapsed/refractory multiple myeloma. Because pomalidomide is extensively metabolized prior to...

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Podrobná bibliografie
Vydáno v:Clin Pharmacol Drug Dev
Hlavní autoři: Li, Yan, Wang, Xiaomin, Liu, Liangang, Zhang, Chengyue, Gomez, Diana, Reyes, Josephine, Palmisano, Maria, Zhou, Simon
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585766/
https://ncbi.nlm.nih.gov/pubmed/29746728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.470
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