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Exo1 independent DNA mismatch repair involves multiple compensatory nucleases
Functional DNA mismatch repair (MMR) is essential for maintaining the fidelity of DNA replication and genetic stability. In hematopoiesis, loss of MMR results in methylating agent resistance and a hematopoietic stem cell (HSC) repopulation defect. Additionally MMR failure is associated with a variet...
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| Publicado no: | DNA Repair (Amst) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5944346/ https://ncbi.nlm.nih.gov/pubmed/25037770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.06.005 |
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