NLRP3 Inflammasome and Caspase-1/11 Pathway Orchestrate Different Outcomes in the Host Protection Against Trypanosoma cruzi Acute Infection

Infection with protozoan parasite Trypanosoma cruzi results in activation of nucleotide-binding domain and leucine-rich repeat containing receptors (NLRs). NLR activation leads to inflammasome formation, the activation of caspase-1, and the subsequent cleavage of IL-1β and IL-18. Considering that in...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Paroli, Augusto F., Gonzalez, Patricia V., Díaz-Luján, Cintia, Onofrio, Luisina I., Arocena, Alfredo, Cano, Roxana C., Carrera-Silva, Eugenio A., Gea, Susana
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944318/
https://ncbi.nlm.nih.gov/pubmed/29774028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00913
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados