Trypanosoma cruzi Infection Is a Potent Risk Factor for Non-alcoholic Steatohepatitis Enhancing Local and Systemic Inflammation Associated with Strong Oxidative Stress and Metabolic Disorders

BACKGROUND: The immune mechanisms underlying experimental non-alcoholic steatohepatitis (NASH), and more interestingly, the effect of T. cruzi chronic infection on the pathogenesis of this metabolic disorder are not completely understood. METHODOLOGY/PRINCIPAL FINDINGS: We evaluated immunological pa...

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Опубликовано в: :PLoS Negl Trop Dis
Главные авторы: Onofrio, Luisina I., Arocena, Alfredo R., Paroli, Augusto F., Cabalén, María E., Andrada, Marta C., Cano, Roxana C., Gea, Susana
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323252/
https://ncbi.nlm.nih.gov/pubmed/25668433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003464
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