Exploring local solvation environments of a heme protein using the spectroscopic reporter 4-cyano-l-phenylalanine

The vibrational reporter unnatural amino acid (UAA) 4-cyano-l-phenylalanine (pCNF) was genetically incorporated individually at three sites (5, 36, and 78) in the heme protein Caldanaerobacter subterraneus H-NOX to probe local hydration environments. The UAA pCNF was incorporated site-specifically u...

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Publicat a:RSC Adv
Autors principals: Kearney, Caroline, Olenginski, Lukasz T., Hirn, Trexler D., Fowler, Gwendolyn D., Tariq, Daniyal, Brewer, Scott H., Phillips-Piro, Christine M.
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society of Chemistry 2018
Matèries:
Chemistry
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944249/
https://ncbi.nlm.nih.gov/pubmed/29780583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ra02000k
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