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Mechanistic perspective and functional activity of insulin in amylin aggregation

Insulin is a key regulatory polypeptide that is secreted from pancreatic β-cells and has several important effects on the synthesis of lipids, regulation of enzymatic activities, blood glucose levels and the prevention of hyperglycemia. Insulin was demonstrated to self-assemble into ordered amyloid...

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Bibliografiske detaljer
Udgivet i:Chem Sci
Main Authors: Baram, Michal, Gilead, Sharon, Gazit, Ehud, Miller, Yifat
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944211/
https://ncbi.nlm.nih.gov/pubmed/29780554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc00481a
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