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Novel insights into amylin aggregation

Amylin is a peptide that aggregates into species that are toxic to pancreatic beta cells, leading to type II diabetes. This study has for the first time quantified amylin association and dissociation kinetics (association constant (k(a)) = 28.7 ± 5.1 L mol(−1) s(−1) and dissociation constant (k(d))...

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Bibliografiske detaljer
Udgivet i:Biotechnol Biotechnol Equip
Main Authors: Pillay, Karen, Govender, Patrick
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434089/
https://ncbi.nlm.nih.gov/pubmed/26019498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13102818.2014.901680
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