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Benzbromarone, Quercetin, and Folic Acid Inhibit Amylin Aggregation

Human Amylin, or islet amyloid polypeptide (hIAPP), is a small hormone secreted by pancreatic β-cells that forms aggregates under insulin deficiency metabolic conditions, and it constitutes a pathological hallmark of type II diabetes mellitus. In type II diabetes patients, amylin is abnormally incre...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: López, Laura C., Varea, Olga, Navarro, Susanna, Carrodeguas, José A., Sanchez de Groot, Natalia, Ventura, Salvador, Sancho, Javier
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926496/
https://ncbi.nlm.nih.gov/pubmed/27322259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17060964
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