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Benzbromarone, Quercetin, and Folic Acid Inhibit Amylin Aggregation
Human Amylin, or islet amyloid polypeptide (hIAPP), is a small hormone secreted by pancreatic β-cells that forms aggregates under insulin deficiency metabolic conditions, and it constitutes a pathological hallmark of type II diabetes mellitus. In type II diabetes patients, amylin is abnormally incre...
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Publicado no: | Int J Mol Sci |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
MDPI
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4926496/ https://ncbi.nlm.nih.gov/pubmed/27322259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17060964 |
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