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Flavopiridol Protects Bone Tissue by Attenuating RANKL Induced Osteoclast Formation
Bone resorption and homeostasis is carried out by osteoclasts, whose differentiation and activity are regulated by the RANK/RANKL axis. Our previous studies using a mouse model of joint injury show that joint trauma induces local inflammation followed by bone remodeling. The transcription factor cyc...
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| Publicado no: | Front Pharmacol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5944179/ https://ncbi.nlm.nih.gov/pubmed/29773986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00174 |
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