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Cyclin-Dependent Kinase 9 inhibition protects cartilage from the catabolic effects of pro-inflammatory cytokines
OBJECTIVE: CDK9 controls the activation of primary inflammatory response genes. We determined whether CDK9 inhibition protects cartilage from the catabolic effects of pro-inflammatory cytokines. METHODS: Human chondrocytes were challenged with different pro-inflammatory stimuli (IL-1β, lipopolysacch...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4127300/ https://ncbi.nlm.nih.gov/pubmed/24470357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38378 |
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