Methylglyoxal Disrupts Paranodal Axoglial Junctions via Calpain Activation

Nodes of Ranvier and associated paranodal and juxtaparanodal domains along myelinated axons are essential for normal function of the peripheral and central nervous systems. Disruption of these domains as well as increases in the reactive carbonyl species methylglyoxal are implicated as a pathophysio...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ASN Neuro
Prif Awduron: Griggs, Ryan B., Yermakov, Leonid M., Drouet, Domenica E., Nguyen, Duc V.M., Susuki, Keiichiro
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: SAGE Publications 2018
Pynciau:
Original Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944142/
https://ncbi.nlm.nih.gov/pubmed/29673258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1759091418766175
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