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Methylglyoxal Disrupts Paranodal Axoglial Junctions via Calpain Activation

Nodes of Ranvier and associated paranodal and juxtaparanodal domains along myelinated axons are essential for normal function of the peripheral and central nervous systems. Disruption of these domains as well as increases in the reactive carbonyl species methylglyoxal are implicated as a pathophysio...

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Detalhes bibliográficos
Publicado no:ASN Neuro
Main Authors: Griggs, Ryan B., Yermakov, Leonid M., Drouet, Domenica E., Nguyen, Duc V.M., Susuki, Keiichiro
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944142/
https://ncbi.nlm.nih.gov/pubmed/29673258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1759091418766175
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