SUMOylation regulates p27(Kip1) stability and localization in response to TGFβ

Exposure of normal and tumor-derived cells to TGFβ results in different outcomes, depending on the regulation of key targets. The CDK inhibitor p27(Kip1) is one of these TGFβ targets and is essential for the TGFβ-induced cell cycle arrest. TGFβ treatment inhibits p27(Kip1) degradation and induces it...

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Detaylı Bibliyografya
Yayımlandı:J Mol Cell Biol
Asıl Yazarlar: Lovisa, Sara, Citro, Simona, Sonego, Maura, Dall'Acqua, Alessandra, Ranzuglia, Valentina, Berton, Stefania, Colombatti, Alfonso, Belletti, Barbara, Chiocca, Susanna, Schiappacassi, Monica, Baldassarre, Gustavo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2016
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943672/
https://ncbi.nlm.nih.gov/pubmed/26450989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjv056
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