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SUMOylation regulates p27(Kip1) stability and localization in response to TGFβ
Exposure of normal and tumor-derived cells to TGFβ results in different outcomes, depending on the regulation of key targets. The CDK inhibitor p27(Kip1) is one of these TGFβ targets and is essential for the TGFβ-induced cell cycle arrest. TGFβ treatment inhibits p27(Kip1) degradation and induces it...
Kaydedildi:
| Yayımlandı: | J Mol Cell Biol |
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| Asıl Yazarlar: | , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5943672/ https://ncbi.nlm.nih.gov/pubmed/26450989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjv056 |
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