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The Tumor Suppressor Functions of p27(kip1) Include Control of the Mesenchymal/Amoeboid Transition
In many human cancers, p27 downregulation correlates with a worse prognosis, suggesting that p27 levels could represent an important determinant in cell transformation and cancer development. Using a mouse model system based on v-src-induced transformation, we show here that p27 absence is always li...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2738297/ https://ncbi.nlm.nih.gov/pubmed/19596789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00144-09 |
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