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Novel Heparin Mimetics Reveal Cooperativity Between Exosite 2 and Sodium-Binding Site of Thrombin
INTRODUCTION: Thrombin is a primary target of most anticoagulants. Yet, thrombin’s dual and opposing role in pro- as well as anti- coagulant processes imposes considerable challenges in discovering finely tuned regulators that maintain homeostasis, rather than disproportionately changing the equilib...
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| Veröffentlicht in: | Thromb Res |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5943173/ https://ncbi.nlm.nih.gov/pubmed/29573721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2018.03.013 |
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