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High mutation rates limit evolutionary adaptation in Escherichia coli
Mutation is fundamental to evolution, because it generates the genetic variation on which selection can act. In nature, genetic changes often increase the mutation rate in systems that range from viruses and bacteria to human tumors. Such an increase promotes the accumulation of frequent deleterious...
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| Publicado no: | PLoS Genet |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5942850/ https://ncbi.nlm.nih.gov/pubmed/29702649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007324 |
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