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Competition between high- and higher-mutating strains of Escherichia coli

Experimental studies have shown that a mutator allele can readily hitchhike to fixation with beneficial mutations in an asexual population having a low, wild-type mutation rate. Here, we show that a genotype bearing two mutator alleles can supplant a population already fixed for one mutator allele....

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Autors principals: Gentile, Christopher F., Yu, Szi-Chieh, Serrano, Sebastian Akle, Gerrish, Philip J., Sniegowski, Paul D.
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097864/
https://ncbi.nlm.nih.gov/pubmed/21227974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsbl.2010.1036
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