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Structural basis for membrane anchoring and fusion regulation of the Herpes Simplex Virus fusogen gB

Viral fusogens merge viral and cell membranes during cell penetration. Their ectodomains drive fusion by undergoing large-scale refolding, but little is known about the functionally important regions located within or near the membrane. Here, we report the crystal structure of the full-length glycop...

詳細記述

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書誌詳細
出版年:Nat Struct Mol Biol
主要な著者: Cooper, Rebecca S., Georgieva, Elka R., Borbat, Peter P., Freed, Jack H., Heldwein, Ekaterina E.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5942590/
https://ncbi.nlm.nih.gov/pubmed/29728654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0060-6
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