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Markov models for the elucidation of allosteric regulation

Allosteric regulation refers to the process where the effect of binding of a ligand at one site of a protein is transmitted to another, often distant, functional site. In recent years, it has been demonstrated that allosteric mechanisms can be understood by the conformational ensembles of a protein....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Philos Trans R Soc Lond B Biol Sci
Hauptverfasser: Sengupta, Ushnish, Strodel, Birgit
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5941173/
https://ncbi.nlm.nih.gov/pubmed/29735732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2017.0178
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