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Additional mitochondrial DNA influences the interactions between the nuclear and mitochondrial genomes in a bovine embryo model of nuclear transfer

We generated cattle embryos using mitochondrial supplementation and somatic cell nuclear transfer (SCNT), named miNT, to determine how additional mitochondrial DNA (mtDNA) modulates the nuclear genome. To eliminate any confounding effects from somatic cell mtDNA in intraspecies SCNT, donor cell mtDN...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Srirattana, Kanokwan, St. John, Justin C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940817/
https://ncbi.nlm.nih.gov/pubmed/29740154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25516-3
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