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Global DNA methylation synergistically regulates the nuclear and mitochondrial genomes in glioblastoma cells

Replication of mitochondrial DNA is strictly regulated during differentiation and development allowing each cell type to acquire its required mtDNA copy number to meet its specific needs for energy. Undifferentiated cells establish the mtDNA set point, which provides low numbers of mtDNA copy but su...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Sun, Xin, Johnson, Jacqueline, St. John, Justin C
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158714/
https://ncbi.nlm.nih.gov/pubmed/29722878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky339
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