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Bile acids and their respective conjugates elicit different responses in neonatal cardiomyocytes: role of Gi protein, muscarinic receptors and TGR5

Bile acids are recognised as bioactive signalling molecules. While they are known to influence arrhythmia susceptibility in cholestasis, there is limited knowledge about the underlying mechanisms. To delineate mechanisms underlying fetal heart rhythm disturbances in cholestatic pregnancy, we used FR...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Ibrahim, Effendi, Diakonov, Ivan, Arunthavarajah, Dulasi, Swift, Teresa, Goodwin, Mary, McIlvride, Saraid, Nikolova, Vanya, Williamson, Catherine, Gorelik, Julia
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940781/
https://ncbi.nlm.nih.gov/pubmed/29740092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25569-4
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