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Overexpression of Prostaglandin E2 EP4 Receptor Improves Cardiac Function after Myocardial Infarction

BACKGROUND: Prostaglandin E2 (PGE(2)) signals through 4 separate G-protein coupled receptor sub-types to elicit a variety of physiologic and pathophysiological effects. We recently reported that PGE(2) via its EP3 receptor could reduce cardiac contractility of isolated myocytes and the working heart...

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Bibliographische Detailangaben
Veröffentlicht in:J Mol Cell Cardiol
Hauptverfasser: Bryson, Timothy D., Gu, Xiaosong, Khalil, Remonda M., Khan, Safa, Zhu, Liping, Xu, Jiang, Peterson, Edward, Yang, Xiao-Ping, Harding, Pamela
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940572/
https://ncbi.nlm.nih.gov/pubmed/29522761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2018.03.005
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