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Fractalkine neutralization improves cardiac function after myocardial infarction

Concentrations of the chemokine fractalkine (FKN) are increased in patients with chronic heart failure, and our previous studies show that aged mice lacking the prostaglandin E(2) EP4 receptor subtype (EP4-KO) have increased cardiac FKN, with a phenotype of dilated cardiomyopathy. However, how FKN p...

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Detalhes bibliográficos
Publicado no:Exp Physiol
Main Authors: Gu, Xiaosong, Xu, Jiang, Yang, Xiao-Ping, Peterson, Edward, Harding, Pamela
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686137/
https://ncbi.nlm.nih.gov/pubmed/25943588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/EP085104
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